Methyl 2-((3S)-6-((1R)-4-(2,6-dimethyl-4-((tetrahydrofuran-2-yl)methoxy)phenyl)-7-fluoro-2,3-dihydro-1H-inden-1-yloxy)-2,3-dihydrobenzofuran-3-yl)acetate → 2-((3S)-6-((1R)-4-(2,6-dimethyl-4-((tetrahydrofuran-2-yl)methoxy)phenyl)-7-fluoro-2,3-dihydro-1H-inden-1-yloxy)-2,3-dihydrobenzofuran-3-yl)acetic acid
반응식
[CH3:1][C:2]1[CH:7]=[C:6]([O:8][CH2:9][CH:10]2[CH2:14][CH2:13][CH2:12][O:11]2)[CH:5]=[C:4]([CH3:15])[C:3]=1[C:16]1[CH:24]=[CH:23][C:22]([F:25])=[C:21]2[C:17]=1[CH2:18][CH2:19][C@H:20]2[O:26][C:27]1[CH:40]=[CH:39][C:30]2[C@H:31]([CH2:34][C:35]([O:37]C)=[O:36])[CH2:32][O:33][C:29]=2[CH:28]=1>C(O)(C)C>[CH3:15][C:4]1[CH:5]=[C:6]([O:8][CH2:9][CH:10]2[CH2:14][CH2:13][CH2:12][O:11]2)[CH:7]=[C:2]([CH3:1])[C:3]=1[C:16]1[CH:24]=[CH:23][C:22]([F:25])=[C:21]2[C:17]=1[CH2:18][CH2:19][C@H:20]2[O:26][C:27]1[CH:40]=[CH:39][C:30]2[C@H:31]([CH2:34][C:35]([OH:37])=[O:36])[CH2:32][O:33][C:29]=2[CH:28]=1참가 물질
3
반응물 1
생성물 1
시약·촉매·용매 1
실험 절차
The title compound is prepared from methyl 2-((3S)-6-((1R)-4-(2,6-dimethyl-4-((tetrahydrofuran-2-yl)methoxy)phenyl)-7-fluoro-2,3-dihydro-1H-inden-1-yloxy)-2,3-dihydrobenzofuran-3-yl)acetate following a procedure analogous to that described in example 1. Isopropanol is used instead of methanol. LC (method 1): tR=1.42 min; Mass spectrum (ESI+): m/z=533 [M+H]+.