1-Methylpyrrolidine-2,3-dione → HCID 73455138, 화합물

HRID 2379093노트

반응식

HRID 2379093 반응식
[N:1]([O-:3])=O.[Na+].[CH3:5][N:6]1[CH2:10][CH2:9][C:8](=[O:11])[C:7]1=[O:12]>O>[CH3:5][N:6]1[CH2:10][C:9](=[N:1][OH:3])[C:8](=[O:11])[C:7]1=[O:12]

참가 물질

4

반응물 2

HCID 122113481-Methylpyrrolidine-2,3-dioneHCID 23668193Sodium Nitrite

생성물 1

HCID 73455138HCID 73455138, 화합물수율 58%

시약·촉매·용매 1

HCID 962Water용매

실험 절차

10.5 g (0.15 mol) of sodium nitrite in 50 ml of water are added dropwise at 0° C. to a solution of 17.0 g (0.15 mol) of 1-methyl-2,3-pyrrolidinedione (H. Rapoport et al., J. Org. Chem. 40 (1975) 1264). The mixture is stirred for a further 2 hours, the deposited product is filtered off and 12.0 g (58%) of 1-methyl-2,3,4-pyrrolidinetrione-4-oxime are obtained.

후처리

  1. filtrationthe deposited product is filtered off

출처 및 근거

ORD 기록
ord-80871d6c919e4d6ca0f5f6fcf34e0a0c
출처 데이터셋
uspto-grants-1994_11
특허 번호
US05360812

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