Guanidine → N-carbamimidoyl-3-chloro-4-piperidin-1-ylbenzamide;hydrochloride

HRID 2379725

반응식

[Cl:1][C:2]1[CH:3]=[C:4]([CH:8]=[CH:9][C:10]=1[N:11]1[CH2:16][CH2:15][CH2:14][CH2:13][CH2:12]1)[C:5](O)=[O:6].[NH2:17][C:18]([NH2:20])=[NH:19]>>[ClH:1].[Cl:1][C:2]1[CH:3]=[C:4]([CH:8]=[CH:9][C:10]=1[N:11]1[CH2:16][CH2:15][CH2:14][CH2:13][CH2:12]1)[C:5]([NH:19][C:18]([NH2:20])=[NH:17])=[O:6]

참가 물질

반응물 2

HCID 3520Guanidine

HCID 189562313-Chloro-4-(piperidin-1-yl)benzoic acid

생성물 1

HCID 178479493N-carbamimidoyl-3-chloro-4-piperidin-1-ylbenzamide;hydrochloride

실험 절차

From 3-chloro-4-piperidinobenzoic acid and guanidine (procedure B), colorless crystals, m.p. 155° C.,

출처 및 근거

ORD 기록: ord-023bfc4842b34a1a9e3c2a7de9ae7d19
출처 데이터셋: uspto-grants-1994_11
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US05364868

연결된 노트

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