Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 238058생성일: 2026년 10월 27일
Water → 3-(naphthalen-2-yl)-1-((E)-3-phenylprop-1-enyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
https://huagongshe.com/reaction/238058
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Water | HCID 962 | — |
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 반응물 | Cinnamyl bromide | HCID 5357478 | — |
| 반응물 | HCID 178508705 | HCID 178508705 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 생성물 | 3-(naphthalen-2-yl)-1-((E)-3-phenylprop-1-enyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine | HCID 86617017 | — |
반응 단계
3-(naphthalen-2-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine (50 mg, 0.21 mmol) was dissolved in DMF (1.5 mL) and K2CO3 (110 mg, 0.8 mmol) and 1-((E)-3-bromoprop-1-enyl)benzene were added. The reaction was heated to 60° C. overnight, then cooled to RT and poured into water (30 mL). The precipitate was collected by filtration. ESI-MS (M+H)+ m/z calcd 378.2, found 378.2.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| 특허 번호 | US08642604B2 |
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| 출처 데이터셋 | uspto-grants-2014_02 |
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| ORD ID | ord-8f19ef9f4fba4ff18a7d75e0333bae0c |
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| 출처 메모 | uspto-grants-2014_02 |
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