Leu-phe → L-Phenylalanyl-L-leucine

HRID 2380769

반응식

[NH:1]1[C:18](=[O:19])[C@H:10]([CH2:11][C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)[NH:9][C:7](=[O:8])[C@@H:2]1[CH2:3][CH:4]([CH3:6])[CH3:5].N[C@H](C(N[C@H](C(O)=O)CC1C=CC=CC=1)=[O:27])CC(C)C>>[NH2:9][C@H:10]([C:18]([NH:1][C@H:2]([C:7]([OH:27])=[O:8])[CH2:3][CH:4]([CH3:6])[CH3:5])=[O:19])[CH2:11][C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1

참가 물질

반응물 2

HCID 6992310Leu-phe

HCID 7076347cyclo(L-leucyl-L-phenylalanyl)

생성물 1

HCID 76808L-Phenylalanyl-L-leucine

실험 절차

As a result, it was confirmed that 6.8 mg/l cyclo(L-Leu-L-Phe), 28.7 mg/l L-Leu-L-Phe and 18.5 mg/l L-Phe-L-Leu were formed. No cyclopeptide or straight-chain peptide was detected in the reaction mixture without ATP incubated in the same manner.

출처 및 근거

ORD 기록: ord-c4b343e94a0e471db7cdf61c4f6f351e
출처 데이터셋: uspto-grants-2012_09
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08257943B2

연결된 노트

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