Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Trimethylsilylacetylene → 5-Trimethylsilanylethynyl-1H-indazole
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Trimethylsilylacetylene | HCID 66111 | — |
| 반응물 | 5-Iodo-1H-indazole | HCID 21894739 | — |
| 생성물 | 5-Trimethylsilanylethynyl-1H-indazole | HCID 57950741 | 46% |
반응 단계
In an adaption of GP 8a, 5-Iodo-1H-indazole (0.98 g, 4.02 mmol) was reacted with trimethylsilyl acetylene (0.60 mL, 4.22 mmol) at 90° C. for 5 h to give 395 mg (46%) of pure 5-(trimethylsilyl)ethynyl-1H-indazole.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08642611B2 |
| 출처 데이터셋 | uspto-grants-2014_02 |
| ORD ID | ord-d97e33d95d5b435aabfb6172bc657155 |
| 출처 메모 | uspto-grants-2014_02 |