Furfurylamine → HCID 25213752, 화합물

반응식

Cl[C:2]1[N:7]2[N:8]=[C:9]([NH:11][C:12](=[O:19])[C:13]3[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=3)[N:10]=[C:6]2[CH:5]=[CH:4][CH:3]=1.[CH2:20]([NH2:26])[C:21]1[O:25][CH:24]=[CH:23][CH:22]=1>>[O:25]1[CH:24]=[CH:23][CH:22]=[C:21]1[CH2:20][NH:26][C:2]1[N:7]2[N:8]=[C:9]([NH:11][C:12](=[O:19])[C:13]3[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=3)[N:10]=[C:6]2[CH:5]=[CH:4][CH:3]=1

참가 물질

반응물 2

HCID 3438Furfurylamine

HCID 25212515HCID 25212515, 화합물

생성물 1

HCID 25213752HCID 25213752, 화합물

실험 절차

The title compound was prepared following procedure described for example 30 but starting from N-(5-chloro[1,2,4]triazolo[1,5-a]pyridin-2-yl)benzamide ((B3), 50 mg; 0.18 mmol; 1.0 eq.) and furfurylamine (1.0 mL) as a beige powder (31 mg, 51%). HPLC, Rt: 2.20 min. (purity 94.1%). LC/MS, M+(ESI): 334.1, M−(ESI): 332.1.

출처 및 근거

ORD 기록: ord-d3216a11c92d45b7b6afcc94574355be
출처 데이터셋: uspto-grants-2012_09
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08263595B2

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