Triethylamine → HCID 86684866, 화합물

HRID 238363

반응식

HRID 238363 반응식
C(N(CC)CC)C.[CH3:8][N:9]1[C:13]([NH2:14])=[CH:12][CH:11]=[N:10]1.[CH:15]1[C:24]2[C:19](=[CH:20][CH:21]=[CH:22][CH:23]=2)[CH:18]=[C:17]2[C:25]([O:27][C:28](=O)[C:16]=12)=[O:26]>C1(C)C=CC=CC=1>[CH3:8][N:9]1[C:13]([N:14]2[C:28](=[O:27])[C:16]3[CH:15]=[C:24]4[CH:23]=[CH:22][CH:21]=[CH:20][C:19]4=[CH:18][C:17]=3[C:25]2=[O:26])=[CH:12][CH:11]=[N:10]1

참가 물질

5

반응물 3

HCID 8471TriethylamineHCID 69743Naphtho(2,3-c)furan-1,3-dioneHCID 1369272-Methyl-2H-pyrazol-3-ylamine

생성물 1

HCID 86684866HCID 86684866, 화합물수율 87.6%

시약·촉매·용매 1

HCID 1140Toluene용매

실험 절차

Triethylamine (1.10 mL) was added to a toluene (14 mL) suspension that contained 1-methyl-1H-pyrazol-5-amine (400 mg) and 2,3-naphthalenedicarboxylic anhydride (816 mg), and the obtained solution was then heated to reflux for 2 hours. Thereafter, the reaction solution was cooled to a room temperature, and the precipitated solid was then collected by filtration. The collected solid was washed with ethyl acetate, so as to obtain the title compound (1.00 g) in the form of a colorless solid.

후처리

  1. temperaturethe obtained solution was then heated
  2. temperatureto reflux for 2 hours
  3. filtrationthe precipitated solid was then collected by filtration
  4. washThe collected solid was washed with ethyl acetate

출처 및 근거

ORD 기록
ord-788b2b43ce4b47b5a5a35bfe3df41dd7
출처 데이터셋
uspto-grants-2014_02
특허 번호
US08642626B2

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