Triethylamine → 2-(1-Methyl-1H-pyrazol-5-yl)-1H-benzo[f]isoindol-1,3(2H)-dione

반응식

C(N(CC)CC)C.[CH3:8][N:9]1[C:13]([NH2:14])=[CH:12][CH:11]=[N:10]1.[CH:15]1[C:24]2[C:19](=[CH:20][CH:21]=[CH:22][CH:23]=2)[CH:18]=[C:17]2[C:25]([O:27][C:28](=O)[C:16]=12)=[O:26]>C1(C)C=CC=CC=1>[CH3:8][N:9]1[C:13]([N:14]2[C:28](=[O:27])[C:16]3[CH:15]=[C:24]4[CH:23]=[CH:22][CH:21]=[CH:20][C:19]4=[CH:18][C:17]=3[C:25]2=[O:26])=[CH:12][CH:11]=[N:10]1

참가 물질

실험 절차

Triethylamine (1.10 mL) was added to a toluene (14 mL) suspension that contained 1-methyl-1H-pyrazol-5-amine (400 mg) and 2,3-naphthalenedicarboxylic anhydride (816 mg), and the obtained solution was then heated to reflux for 2 hours. Thereafter, the reaction solution was cooled to a room temperature, and the precipitated solid was then collected by filtration. The collected solid was washed with ethyl acetate, so as to obtain the title compound (1.00 g) in the form of a colorless solid.