HCID 9118520, 화합물 → HCID 57883560, 화합물
반응식
C(OC(=O)[CH:5]([S:7][C:8]1[S:12][C:11]([NH:13][C:14]([N:16]([CH:22]2[CH2:28][CH2:27][CH2:26][CH2:25][CH2:24][CH2:23]2)[CH:17]2[CH2:21][CH2:20][CH2:19][CH2:18]2)=[O:15])=[N:10][CH:9]=1)[CH3:6])C.C1(NC2CCCC2)CCCCCC1.NC1SC=NC=1.C([O:51][C:52](=[O:55])CS)C>>[CH:22]1([N:16]([CH:17]2[CH2:18][CH2:19][CH2:20][CH2:21]2)[C:14](=[O:15])[NH:13][C:11]2[S:12][C:8]([S:7][CH2:5][CH2:6][C:52]([OH:55])=[O:51])=[CH:9][N:10]=2)[CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28]1참가 물질
4
실험 절차
[2-(3-Cycloheptyl-3-cyclopentyl-ureido)-thiazol-5-ylsulfanyl]-propionic acid ethyl ester prepared as described in general procedure (A) using cycloheptyl-cyclopentylamine and 5-aminothiazole-2-mercaptoacetic acid ethyl ester. Hydrolysis using general procedure (F) gave the title compound