Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Water → N-[3-bromo-5-(trifluoromethyl)phenyl]acetamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Water | HCID 962 | — |
| 반응물 | Acetic Anhydride | HCID 7918 | — |
| 반응물 | 3-Bromo-5-(trifluoromethyl)aniline | HCID 2735880 | — |
| 용매 | Acetic Acid | HCID 176 | — |
| 생성물 | N-[3-bromo-5-(trifluoromethyl)phenyl]acetamide | HCID 21959349 | — |
반응 단계
3-Bromo-5-(trifluoromethyl)phenylamine (5 g, Alfa-Aesar) was dissolved in AcOH (140 ml) and Ac2O (5.9 ml, Aldrich) was added. The reaction was stirred at RT overnight. The mixture was added slowly to H2O (˜700 ml) forming a white precipitate. The solid was isolated by filtration, washed with H2O and dried under vacuum to yield N-(3-bromo-5-trifluoromethyl-phenyl)-acetamide.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08642624B2 |
| 출처 데이터셋 | uspto-grants-2014_02 |
| ORD ID | ord-d362e81504494fc290da42d0f1a2643c |
| 출처 메모 | uspto-grants-2014_02 |