5-Bromosalicylic acid → 5-Bromo-N-[4,5-bis(furan-2-yl)oxazol-2-yl]-2-hydroxybenzamide

HRID 2384336노트

반응식

HRID 2384336 반응식
[Br:1][C:2]1[CH:10]=[C:6]([C:7]([OH:9])=O)[C:5]([OH:11])=[CH:4][CH:3]=1.[NH2:12][C:13]1[O:14][C:15]([C:23]2[O:24][CH:25]=[CH:26][CH:27]=2)=[C:16]([C:18]2[O:19][CH:20]=[CH:21][CH:22]=2)[N:17]=1>>[Br:1][C:2]1[CH:3]=[CH:4][C:5]([OH:11])=[C:6]([CH:10]=1)[C:7]([NH:12][C:13]1[O:14][C:15]([C:23]2[O:24][CH:25]=[CH:26][CH:27]=2)=[C:16]([C:18]2[O:19][CH:20]=[CH:21][CH:22]=2)[N:17]=1)=[O:9]

참가 물질

3

반응물 2

HCID 69725-Bromosalicylic acidHCID 126152352-Amino-4,5-bis(furan-2-yl)oxazole

생성물 1

HCID 100018725-Bromo-N-[4,5-bis(furan-2-yl)oxazol-2-yl]-2-hydroxybenzamide수율 12.9%

실험 절차

Using 5-bromosalicylic acid and 2-amino-4,5-bis(furan-2-yl)oxazole as the raw materials, the same operation as the example 16 gave the title compound.

출처 및 근거

ORD 기록
ord-8199b27aadf84d0287828abecf0df158
출처 데이터셋
uspto-grants-2012_09
특허 번호
US08263657B2

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