5-Chlorosalicylic Acid → 5-Chloro-N-(6-chloro-4-methoxypyrimidin-2-yl)-2-hydroxybenzamide

HRID 2384339

반응식

HRID 2384339 반응식
[Cl:1][C:2]1[CH:10]=[C:6]([C:7]([OH:9])=O)[C:5]([OH:11])=[CH:4][CH:3]=1.[NH2:12][C:13]1[N:18]=[C:17]([O:19][CH3:20])[CH:16]=[C:15]([Cl:21])[N:14]=1>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([OH:11])=[C:6]([CH:10]=1)[C:7]([NH:12][C:13]1[N:18]=[C:17]([O:19][CH3:20])[CH:16]=[C:15]([Cl:21])[N:14]=1)=[O:9]

참가 물질

3

반응물 2

HCID 94475-Chlorosalicylic AcidHCID 798112-Pyrimidinamine, 4-chloro-6-methoxy-

생성물 1

HCID 99729035-Chloro-N-(6-chloro-4-methoxypyrimidin-2-yl)-2-hydroxybenzamide수율 2.2%

실험 절차

Using 5-chlorosalicylic acid and 2-amino-6-chloro-4-methoxypyrimidine as the raw materials, the same operation as the example 16 gave the title compound.

출처 및 근거

ORD 기록
ord-10e0e434fe034e6485bcd3b1f277de9d
출처 데이터셋
uspto-grants-2012_09
특허 번호
US08263657B2

연결된 노트

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