Benzenamine, 3,5-bis(trifluoromethyl)- → 4-Acetylamino-N-[3,5-bis(trifluoromethyl)phenyl]-5-chloro-2-methoxybenzamide

HRID 2384390노트

반응식

HRID 2384390 반응식
[C:1]([NH:4][C:5]1[C:13]([Cl:14])=[CH:12][C:8]([C:9]([OH:11])=O)=[C:7]([O:15][CH3:16])[CH:6]=1)(=[O:3])[CH3:2].[F:17][C:18]([F:31])([F:30])[C:19]1[CH:20]=[C:21]([CH:23]=[C:24]([C:26]([F:29])([F:28])[F:27])[CH:25]=1)[NH2:22]>>[C:1]([NH:4][C:5]1[C:13]([Cl:14])=[CH:12][C:8]([C:9]([NH:22][C:21]2[CH:23]=[C:24]([C:26]([F:27])([F:28])[F:29])[CH:25]=[C:19]([C:18]([F:17])([F:30])[F:31])[CH:20]=2)=[O:11])=[C:7]([O:15][CH3:16])[CH:6]=1)(=[O:3])[CH3:2]

참가 물질

3

반응물 2

HCID 9480Benzenamine, 3,5-bis(trifluoromethyl)-HCID 109884964-Acetamido-5-chloro-2-methoxybenzoic acid

생성물 1

HCID 178602074-Acetylamino-N-[3,5-bis(trifluoromethyl)phenyl]-5-chloro-2-methoxybenzamide수율 23.8%

실험 절차

Using 4-acetylamino-5-chloro-2-methoxybenzoic acid and 3,5-bis(trifluoromethyl)aniline as the raw materials, the same operation as the example 24 gave the title compound.

출처 및 근거

ORD 기록
ord-4b423f8405964365b1679c648dcdce8d
출처 데이터셋
uspto-grants-2012_09
특허 번호
US08263657B2

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