5-Chlorosalicylic Acid → 5-Chloro-N-[4-chloro-2-(trifluoromethyl)phenyl]-2-hydroxybenzamide

HRID 2384398노트

반응식

HRID 2384398 반응식
[Cl:1][C:2]1[CH:10]=[C:6]([C:7]([OH:9])=O)[C:5]([OH:11])=[CH:4][CH:3]=1.[Cl:12][C:13]1[CH:19]=[CH:18][C:16]([NH2:17])=[C:15]([C:20]([F:23])([F:22])[F:21])[CH:14]=1>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([OH:11])=[C:6]([CH:10]=1)[C:7]([NH:17][C:16]1[CH:18]=[CH:19][C:13]([Cl:12])=[CH:14][C:15]=1[C:20]([F:23])([F:21])[F:22])=[O:9]

참가 물질

3

반응물 2

HCID 94475-Chlorosalicylic AcidHCID 67961Benzenamine, 4-chloro-2-(trifluoromethyl)-

생성물 1

HCID 178603145-Chloro-N-[4-chloro-2-(trifluoromethyl)phenyl]-2-hydroxybenzamide수율 21.5%

실험 절차

Using 5-chlorosalicylic acid and 4-chloro-2-(trifluoromethyl)aniline as the raw materials, the same operation as the example 16 gave the title compound.

출처 및 근거

ORD 기록
ord-dc0002e0fbe54ee8ab134378c582f011
출처 데이터셋
uspto-grants-2012_09
특허 번호
US08263657B2

반응 노트

불러오는 중…