5-Chlorosalicylic Acid → 5-Chloro-2-hydroxy-N-[4-nitro-3-(trifluoromethyl)phenyl]benzamide

HRID 2384408

반응식

HRID 2384408 반응식
[Cl:1][C:2]1[CH:10]=[C:6]([C:7]([OH:9])=O)[C:5]([OH:11])=[CH:4][CH:3]=1.[N+:12]([C:15]1[CH:21]=[CH:20][C:18]([NH2:19])=[CH:17][C:16]=1[C:22]([F:25])([F:24])[F:23])([O-:14])=[O:13]>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([OH:11])=[C:6]([CH:10]=1)[C:7]([NH:19][C:18]1[CH:20]=[CH:21][C:15]([N+:12]([O-:14])=[O:13])=[C:16]([C:22]([F:23])([F:24])[F:25])[CH:17]=1)=[O:9]

참가 물질

3

반응물 2

HCID 94475-Chlorosalicylic AcidHCID 949554-Nitro-3-(trifluoromethyl)aniline

생성물 1

HCID 178602585-Chloro-2-hydroxy-N-[4-nitro-3-(trifluoromethyl)phenyl]benzamide수율 44.8%

실험 절차

Using 5-chlorosalicylic acid and 4-nitro-3-(trifluoromethyl)aniline as the raw materials, the same operation as the example 16 gave the title compound.

출처 및 근거

ORD 기록
ord-465f329de2104da49971401ac18bd06b
출처 데이터셋
uspto-grants-2012_09
특허 번호
US08263657B2

연결된 노트

불러오는 중…