1-(2-Chloroethyl)pyrrolidine → 1-[2-(5-Nitro-2-trifluoromethylphenoxy)ethyl]-pyrrolidine

반응식

[N+:1]([C:4]1[CH:5]=[CH:6][C:7]([C:11]([F:14])([F:13])[F:12])=[C:8]([OH:10])[CH:9]=1)([O-:3])=[O:2].Cl[CH2:16][CH2:17][N:18]1[CH2:22][CH2:21][CH2:20][CH2:19]1.C(C1C=CC([N+]([O-])=O)=CC=1OCCN1CCCCC1)(C)(C)C>>[N+:1]([C:4]1[CH:5]=[CH:6][C:7]([C:11]([F:12])([F:13])[F:14])=[C:8]([CH:9]=1)[O:10][CH2:16][CH2:17][N:18]1[CH2:22][CH2:21][CH2:20][CH2:19]1)([O-:3])=[O:2]

참가 물질

반응물 3

HCID 816691-(2-Chloroethyl)pyrrolidine

HCID 219595061-[2-(2-Tert-butyl-5-nitro-phenoxy)-ethyl]-piperidine

HCID 219595865-Nitro-2-(trifluoromethyl)phenol

생성물 1

HCID 219594941-[2-(5-Nitro-2-trifluoromethylphenoxy)ethyl]-pyrrolidine

실험 절차

1-[2-(5-Nitro-2-trifluoromethylphenoxy)ethyl]-pyrrolidine was prepared from 5-nitro-2-trifluoromethyl-phenol and 1-(2-chloroethyl)pyrrolidine by a procedure similar to that described for 1-[2-(2-tert-butyl-5-nitro-phenoxy)-ethyl]-piperidine.

출처 및 근거

ORD 기록: ord-00375ee15b7f4b8b87c66ddaf41cccb2
출처 데이터셋: uspto-grants-2014_02
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08642624B2

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