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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 2384663생성일: 2026년 10월 26일

1-(2,2-Difluoroethyl)piperazine → 5-[1-(4-Chloro-2-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-2-[4-(2,2-difluoro-ethyl)-piperazin-1-yl]-thiazol-4-one

https://huagongshe.com/reaction/2384663

반응식

참여 물질

역할이름HCID투입량
반응물1-(2,2-Difluoroethyl)piperazineHCID 19622797—
반응물5-[1-(4-chloro-2-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-2-ethylsulfanyl-thiazol-4-oneHCID 67240123—
생성물5-[1-(4-Chloro-2-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-2-[4-(2,2-difluoro-ethyl)-piperazin-1-yl]-thiazol-4-oneHCID 76756286—

반응 단계

5-[1-(4-Chloro-2-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-2-[4-(2,2-difluoro-ethyl)-piperazin-1-yl]-thiazol-4-one was prepared from 5-[1-(4-chloro-2-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-2-ethylsulfanyl-thiazol-4-one and 1-(2,2-difluoro-ethyl)piperazine following General Procedure C.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US08263781B2
출처 데이터셋uspto-grants-2012_09
ORD IDord-b1a11522c3ef40e1a741d07a54e5ff4d
출처 메모uspto-grants-2012_09