Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
5-Aminopentan-1-ol → N-(5-hydroxypentyl)-3-(N-vinylformamido)propionamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 5-Aminopentan-1-ol | HCID 75634 | — |
| 반응물 | Sodium Methoxide | HCID 10942334 | — |
| 반응물 | methyl 3-(N-vinylformamido)propionate | HCID 10964771 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | N-(5-hydroxypentyl)-3-(N-vinylformamido)propionamide | HCID 19690346 | — |
반응 단계
The apparatus of Example 2 was charged with 15.7 grams (0.1 mol) of methyl 3-(N-vinylformamido)propionate, 10.3 grams (0.1 mol) of 5-amino-1-pentanol and 0.12 gram of 25% sodium methoxide in methanol solution. The mixture was stirred at 90° C. for 3 hours after which the methanol coproduct was removed by distillation at reduced pressure. NMR analysis of the remaining amber liquid indicated about 69% conversion to the desired product.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05728878 |
| 출처 데이터셋 | uspto-grants-1998_03 |
| ORD ID | ord-575fdaab9b024e09a2ac34fb099e5fd0 |
| 출처 메모 | uspto-grants-1998_03 |