Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Thionyl Chloride → 2-Fluoropyridine-3-carbonyl chloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Thionyl Chloride | HCID 24386 | — |
| 반응물 | 2-Fluoronicotinic acid | HCID 96089 | — |
| 생성물 | 2-Fluoropyridine-3-carbonyl chloride | HCID 21959582 | — |
반응 단계
2-Fluoropyridine-3-carboxylic acid (7 g, Step C) was suspended in SOCl2 (100 mL). After heating under reflux for 2 h, the mixture became homogeneous. Excess SOCl2 was removed in vacuo to afford a brown solid as desired product.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08642624B2 |
| 출처 데이터셋 | uspto-grants-2014_02 |
| ORD ID | ord-9a43b48ccf53428fb07ec0624f068c33 |
| 출처 메모 | uspto-grants-2014_02 |