Methanesulfonyl chloride → HCID 86603249, 화합물

HRID 2386361노트

반응식

HRID 2386361 반응식
[Cl:1][C:2]1[N:7]=[C:6]([C:8]2[CH:9]=[C:10]([CH:20]=[CH:21][CH:22]=2)[CH2:11][NH:12][CH2:13][C:14]2[CH:15]=[N:16][CH:17]=[CH:18][CH:19]=2)[CH:5]=[CH:4][N:3]=1.[CH3:23][S:24](Cl)(=[O:26])=[O:25]>>[Cl:1][C:2]1[N:7]=[C:6]([C:8]2[CH:9]=[C:10]([CH:20]=[CH:21][CH:22]=2)[CH2:11][N:12]([CH2:13][C:14]2[CH:15]=[N:16][CH:17]=[CH:18][CH:19]=2)[S:24]([CH3:23])(=[O:26])=[O:25])[CH:5]=[CH:4][N:3]=1

참가 물질

3

반응물 2

HCID 31297Methanesulfonyl chlorideHCID 86603250[3-(2-Chloro-pyrimidin-4-yl)-benzyl]-pyridin-3-ylmethyl-amine

생성물 1

HCID 86603249HCID 86603249, 화합물

실험 절차

Intermediate 12 was coupled with methanesulfonyl chloride following procedure D. LC-MS showed the product had the expected M+H+ of 389.

출처 및 근거

ORD 기록
ord-1cc855ec35d3488e875352b16b426001
출처 데이터셋
uspto-grants-2012_09
특허 번호
US08268822B2

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