2,4-Dichloropyrimidine → 1-[3-(2-Chloro-pyrimidin-4-yl)-phenyl]-ethanone

HRID 2386402

반응식

HRID 2386402 반응식
[Cl:1][C:2]1[N:7]=[C:6](Cl)[CH:5]=[CH:4][N:3]=1.[C:9]([C:12]1[CH:13]=[C:14](B(O)O)[CH:15]=[CH:16][CH:17]=1)(=[O:11])[CH3:10]>>[Cl:1][C:2]1[N:7]=[C:6]([C:16]2[CH:17]=[C:12]([C:9](=[O:11])[CH3:10])[CH:13]=[CH:14][CH:15]=2)[CH:5]=[CH:4][N:3]=1

참가 물질

3

반응물 2

HCID 775312,4-DichloropyrimidineHCID 27343103-Acetylphenylboronic acid

생성물 1

HCID 249018391-[3-(2-Chloro-pyrimidin-4-yl)-phenyl]-ethanone

실험 절차

2,4 dichloropyrimidine was coupled with 3-acetylphenylboronic acid following procedure A. LC-MS showed the product had the expected M+H+ of 234.

출처 및 근거

ORD 기록
ord-d9060c6ce313468bb5e2ad7a2573fc28
출처 데이터셋
uspto-grants-2012_09
특허 번호
US08268822B2

연결된 노트

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