Isopropylamine → [3-(2-Chloro-pyrimidin-4-yl)-benzyl]-isopropyl-amine
반응식
C(OC(=O)NC[CH2:9][CH2:10][NH:11][CH2:12][C:13]1[CH:18]=[CH:17][CH:16]=[C:15]([C:19]2[CH:24]=[CH:23][N:22]=[C:21]([Cl:25])[N:20]=2)[CH:14]=1)(C)(C)C.[CH:27](N)(C)C>>[Cl:25][C:21]1[N:20]=[C:19]([C:15]2[CH:14]=[C:13]([CH:18]=[CH:17][CH:16]=2)[CH2:12][NH:11][CH:10]([CH3:9])[CH3:27])[CH:24]=[CH:23][N:22]=1참가 물질
3
실험 절차
Intermediate 2 was coupled with isopropylamine following procedure B. LC-MS showed the product had the expected M+H+ of 262.
출처 및 근거
- ORD 기록
- ord-41d9765b78d44e43ada9bf1efa2a43c3
- 출처 데이터셋
- uspto-grants-2012_09
- 특허 번호
- US08268822B2
반응 노트
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