Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-Amino-1-Boc-piperidine → 4-[5-(2-Chloro-pyrimidin-4-yl)-2-fluoro-benzylamino]-piperidine-1-carboxylic acid tert-butyl ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-Amino-1-Boc-piperidine | HCID 1268291 | — |
| 반응물 | 5-(2-Chloro-pyrimidin-4-yl)-2-fluoro-benzaldehyde | HCID 24901981 | — |
| 생성물 | 4-[5-(2-Chloro-pyrimidin-4-yl)-2-fluoro-benzylamino]-piperidine-1-carboxylic acid tert-butyl ester | HCID 86603293 | — |
반응 단계
Intermediate 89 was coupled with 4-Amino-piperidine-1-carboxylic acid tert-butyl ester following procedure B. LC-MS showed the product was >95% pure and had the expected M+H+ of 421.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08268822B2 |
| 출처 데이터셋 | uspto-grants-2012_09 |
| ORD ID | ord-b45e670e9a9147ca9e6b8859f356cb87 |
| 출처 메모 | uspto-grants-2012_09 |