Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Potassium Carbonate → 1-Methyl-2-nitro-4-propoxybenzene
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 반응물 | 3-Nitro-p-cresol | HCID 16271 | — |
| 반응물 | 1-Iodopropane | HCID 33643 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 생성물 | 1-Methyl-2-nitro-4-propoxybenzene | HCID 58764279 | — |
반응 단계
Potassium carbonate (13.5 g, 0.098 mol) followed by 1-iodopropane (9.56 mL, 0.098 mol) were added to a solution of 4-methyl-3-nitro-phenol (15 g, 0.098 mol) in DMF (100 mL). The mixture was stirred for 5 hours and then partitioned between H2O and EtOAc. The organic layer was washed with satd NaHCO3, brine, dried over Na2SO4 and concentrated to a clear oil (17.5 g).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08268835B2 |
| 출처 데이터셋 | uspto-grants-2012_09 |
| ORD ID | ord-4cb59786c59d40de9611c46f70ef2fe4 |
| 출처 메모 | uspto-grants-2012_09 |