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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 2389620생성일: 2026년 10월 25일

N-(4-bromophenyl)-N-methylacetamide → tert-Butyl (4-{[4'-(acetyl-methyl-amino)-4-methoxy-biphenyl-3-ylmethyl]-amino}-cyclohexyl)-methyl-carbamate

https://huagongshe.com/reaction/2389620

반응식

참여 물질

역할이름HCID투입량
반응물N-(4-bromophenyl)-N-methylacetamideHCID 4324567—
반응물3-{[4-(BOC-methyl-amino)-cyclohexylamino]-methyl}-4-methoxy-benzene boronic acidHCID 25208191—
생성물tert-Butyl (4-{[4'-(acetyl-methyl-amino)-4-methoxy-biphenyl-3-ylmethyl]-amino}-cyclohexyl)-methyl-carbamateHCID 59683468—

반응 단계

Boronic acid 4 (650 mg, 1.04 mmol) is coupled to aryl bromide 62 (238 mg, 1.04 mmol) using Method A to give the title compound.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US08273747B2
출처 데이터셋uspto-grants-2012_09
ORD IDord-69f107135fcb4021901b5992a5c2d419
출처 메모uspto-grants-2012_09