참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Hydrochloric Acid | HCID 313 | — |
| 반응물 | Malonic Acid | HCID 867 | — |
| 반응물 | Furfural | HCID 7362 | — |
| 반응물 | Piperidine | HCID 8082 | — |
| 용매 | Water | HCID 962 | — |
| 용매 | Pyridine | HCID 1049 | — |
| 생성물 | 2-Furanacrylic acid | HCID 643402 | 92% |
반응 단계
To a mixture of 2-furfural (500 g, 5.20 mol) and malonic acid (595 g, 5.72 mol) in pyridine (500 mL) was added piperidine (50 mL, 0.505 mol) at room temperature, and the mixture was stirred at 100° C. for 3 hr. The reaction solution was poured into water (1 L) and acidified with 6M hydrochloric acid. The resulting precipitate was collected by filtration to give the title compound (660 g, yield 92%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US08273761B2 |
|---|
| 출처 데이터셋 | uspto-grants-2012_09 |
|---|
| ORD ID | ord-f4f5782bb6ab4fe5b912f3315f5b6e9d |
|---|
| 출처 메모 | uspto-grants-2012_09 |
|---|
