Tert-butyl(4-chloro-2-ethynylphenoxy)acetate → 2-Ethynyl-1-methyl-4-(propylsulfonyl) benzene

HRID 2390139노트

반응식

HRID 2390139 반응식
C(OC(=O)COC1C=CC(Cl)=CC=1C#C)(C)(C)C.C[Si](C)(C)[C:21]#[C:22][C:23]1[CH:28]=[C:27]([S:29]([CH2:32][CH2:33][CH3:34])(=[O:31])=[O:30])[CH:26]=[CH:25][C:24]=1[CH3:35]>>[C:22]([C:23]1[CH:28]=[C:27]([S:29]([CH2:32][CH2:33][CH3:34])(=[O:30])=[O:31])[CH:26]=[CH:25][C:24]=1[CH3:35])#[CH:21]

참가 물질

3

반응물 2

HCID 56594381Tert-butyl(4-chloro-2-ethynylphenoxy)acetateHCID 585220372-Trimethylsilylethynyl-1-methyl-4-(propylsulfonyl)benzene2회

생성물 1

HCID 585220332-Ethynyl-1-methyl-4-(propylsulfonyl) benzene

실험 절차

Following the general method as outlined in Intermediate 3, starting from 2-trimethylsilylethynyl-1-methyl-4-(propylsulfonyl)benzene (Intermediate 39), the title compound was obtained as a brown liquid after purification by column chromatography (silica) eluting with petroleum ether and ethyl acetate.

출처 및 근거

ORD 기록
ord-8c73ee39ac60483981262804de2a8ae4
출처 데이터셋
uspto-grants-2012_09
특허 번호
US08273769B2

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