2-((4-Chlorophenoxy)methyl)oxirane → Phenyl glycidyl ether

HRID 239023

반응식

HRID 239023 반응식
[NH:1]1[CH2:6][CH2:5][CH:4]([CH2:7][NH:8][C:9]([N:11]2[C:15]3[CH:16]=[CH:17][CH:18]=[CH:19][C:14]=3[N:13]([CH2:20][CH3:21])[C:12]2=[O:22])=[O:10])[CH2:3][CH2:2]1.[CH2:23]([O:27][C:28]1[CH:33]=[CH:32][C:31](Cl)=[CH:30][CH:29]=1)[CH:24]1[O:26][CH2:25]1>>[NH:1]1[CH2:6][CH2:5][CH:4]([CH2:7][NH:8][C:9]([N:11]2[C:15]3[CH:16]=[CH:17][CH:18]=[CH:19][C:14]=3[N:13]([CH:20]([CH3:23])[CH3:21])[C:12]2=[O:22])=[O:10])[CH2:3][CH2:2]1.[O:26]1[CH:24]([CH2:23][O:27][C:28]2[CH:29]=[CH:30][CH:31]=[CH:32][CH:33]=2)[CH2:25]1

참가 물질

4

반응물 2

HCID 915152-((4-Chlorophenoxy)methyl)oxiraneHCID 673783613-Ethyl-2-oxo-2,3-dihydro-benzimidazole-1-carboxylic acid (piperidin-4-ylmethyl)-amide

생성물 2

HCID 31217Phenyl glycidyl etherHCID 442491883-isopropyl-2-oxo-N-(piperidin-4-ylmethyl)-2,3-dihydro-1H-benzimidazole-1-carboxamide

실험 절차

The procedure given in Example 104 was followed using 3-ethyl-2-oxo-2,3-dihydro-benzimidazole-1-carboxylic acid (piperidin-4-ylmethyl)-amide and 4-chlorophenyl glycidyl ether as a reactant, instead of 3-isopropyl-2-oxo-2,3-dihydro-benzimidazole-1-carboxylic acid (piperidin-4-ylmethyl)-amide and 1,2-epoxy-3-phenoxypropane, to give the title compound.

출처 및 근거

ORD 기록
ord-01ad03b3390e49c280118d2952129340
출처 데이터셋
uspto-grants-2014_02
특허 번호
US08642772B2

연결된 노트

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