Tert-butyl(4-chloro-2-ethynylphenoxy)acetate → HCID 56595049, 화합물

HRID 2390340노트

반응식

HRID 2390340 반응식
C([O:5][C:6](=[O:18])[CH2:7][O:8][C:9]1[CH:14]=[CH:13][C:12]([Cl:15])=[CH:11][C:10]=1[C:16]#[CH:17])(C)(C)C.Br[C:20]1[CH:21]=[C:22]([S:26]([NH:29][CH2:30][CH2:31][OH:32])(=[O:28])=[O:27])[CH:23]=[N:24][CH:25]=1>>[Cl:15][C:12]1[CH:13]=[CH:14][C:9]([O:8][CH2:7][C:6]([OH:5])=[O:18])=[C:10]([C:16]#[C:17][C:20]2[CH:25]=[N:24][CH:23]=[C:22]([S:26]([NH:29][CH2:30][CH2:31][OH:32])(=[O:28])=[O:27])[CH:21]=2)[CH:11]=1

참가 물질

3

반응물 2

HCID 56594381Tert-butyl(4-chloro-2-ethynylphenoxy)acetate2회HCID 617955235-Bromo-N-(2-hydroxyethyl)-3-pyridinesulfonamide2회

생성물 1

HCID 56595049HCID 56595049, 화합물

실험 절차

Following the general method as outlined in Example 37, starting from tert-butyl(4-chloro-2-ethynyl phenoxy)acetate (Intermediate 3) and 5-bromo-N-(2-hydroxyethyl)pyridine-3-sulfonamide (Intermediate 31), the title compound was obtained as an off-white solid.

출처 및 근거

ORD 기록
ord-cdb32345f8684aad961003be3e67d1f9
출처 데이터셋
uspto-grants-2012_09
특허 번호
US08273769B2

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