HCID 58521854, 화합물 → HCID 46866076, 화합물

반응식

C([O:5][C:6](=[O:19])[CH2:7][O:8][C:9]1[CH:14]=[CH:13][C:12]([C:15]#[N:16])=[CH:11][C:10]=1[C:17]#[CH:18])(C)(C)C.Br[C:21]1[CH:26]=[C:25]([S:27]([CH2:30][CH:31]([CH3:33])[CH3:32])(=[O:29])=[O:28])[CH:24]=[CH:23][C:22]=1[CH3:34]>>[C:15]([C:12]1[CH:13]=[CH:14][C:9]([O:8][CH2:7][C:6]([OH:5])=[O:19])=[C:10]([C:17]#[C:18][C:23]2[CH:24]=[C:25]([S:27]([CH2:30][CH:31]([CH3:32])[CH3:33])(=[O:28])=[O:29])[CH:26]=[CH:21][C:22]=2[CH3:34])[CH:11]=1)#[N:16]

참가 물질

반응물 2

HCID 58521854HCID 58521854, 화합물2회

HCID 58522073Tert-butyl(4-cyano-2-ethynylphenoxy)acetate2회

생성물 1

HCID 46866076HCID 46866076, 화합물

실험 절차

Following the general method as outlined in Example 37, starting from tert-butyl(4-cyano-2-ethynyl phenoxy)acetate (Intermediate 46) and 2-bromo-4-(isobutylsulfonyl)-1-methylbenzene (Intermediate 66), the title compound was obtained as a yellow solid.

출처 및 근거

ORD 기록: ord-98b7499fc22b48d9a0cc1b5853cc4ac2
출처 데이터셋: uspto-grants-2012_09
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08273769B2

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