HCID 58521853, 화합물 → HCID 58521837, 화합물

HRID 2390354노트

반응식

HRID 2390354 반응식
C([O:5][C:6](=[O:19])[CH2:7][O:8][C:9]1[CH:14]=[CH:13][C:12]([C:15]#[N:16])=[CH:11][C:10]=1[C:17]#[CH:18])(C)(C)C.Br[C:21]1[CH:22]=[C:23]([N:27]([CH3:32])[S:28]([CH3:31])(=[O:30])=[O:29])[CH:24]=[N:25][CH:26]=1>>[C:15]([C:12]1[CH:13]=[CH:14][C:9]([O:8][CH2:7][C:6]([OH:5])=[O:19])=[C:10]([C:17]#[C:18][C:21]2[CH:26]=[N:25][CH:24]=[C:23]([N:27]([CH3:32])[S:28]([CH3:31])(=[O:30])=[O:29])[CH:22]=2)[CH:11]=1)#[N:16]

참가 물질

3

반응물 2

HCID 58521853HCID 58521853, 화합물2회HCID 58522073Tert-butyl(4-cyano-2-ethynylphenoxy)acetate2회

생성물 1

HCID 58521837HCID 58521837, 화합물

실험 절차

Following the general method as outlined in Example 35, starting from tert-butyl(4-cyano-2-ethynyl phenoxy)acetate (Intermediate 46) and N-(5-bromopyridin-3-yl)-N-methylmethanesulfonamide (Intermediate 33), the title compound was obtained as an off-white solid.

출처 및 근거

ORD 기록
ord-771873099a7a44fcb19066c649141b6d
출처 데이터셋
uspto-grants-2012_09
특허 번호
US08273769B2

반응 노트

불러오는 중…