Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
8-Isoquinolin-4-yl-quinoxaline-5-carboxylic acid [3-(4-ethyl-piperazin-1-yl)phenyl]-amide → 8-Isoquinolin-4-yl-quinoxaline-5-carboxylic acid (1H-imidazol-2-yl)-amide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 8-Isoquinolin-4-yl-quinoxaline-5-carboxylic acid [3-(4-ethyl-piperazin-1-yl)phenyl]-amide | HCID 44515669 | — |
| 용매 | Dichloromethane methanol | HCID 21226129 | — |
| 생성물 | 8-Isoquinolin-4-yl-quinoxaline-5-carboxylic acid (1H-imidazol-2-yl)-amide | HCID 44515671 | — |
반응 단계
The title compound was prepared in analogy to the procedures described in Example 14 but using 8-isoquinolin-4-yl-quinoxaline-5-carboxylic acid (Example 52) in Step 14.1. Title compound: ESI-MS: 367.0 [M+H]+; TLC: Rf=0.17 (DCM/MeOH, 95:5).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08273882B2 |
| 출처 데이터셋 | uspto-grants-2012_09 |
| ORD ID | ord-8eae1e4ed1c14776b9ad04f92266012b |
| 출처 메모 | uspto-grants-2012_09 |