2-(2-Phenylethyl)oxirane → 1-Amino-4-phenylbutan-2-ol

HRID 2391944노트

반응식

HRID 2391944 반응식
[C:1]1([CH2:7][CH2:8][CH:9]2[CH2:11][O:10]2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[NH3:12].CO>>[NH2:12][CH2:11][CH:9]([OH:10])[CH2:8][CH2:7][C:1]1[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

참가 물질

3

반응물 2

HCID 1359552-(2-Phenylethyl)oxiraneHCID 21705897Ammonia methanol

생성물 1

HCID 157609871-Amino-4-phenylbutan-2-ol

반응 조건

온도
70 °C

실험 절차

2-(2-phenylethyl)oxirane (8.0 g, 54 mmol) was placed in a sealed tube with 7N NH3-MeOH (130 mL) and stirred 2 hours at 70° C. followed by concentration to a clear oil (and was used without further purification in the following step.

후처리

  1. concentrationfollowed by concentration to a clear oil (and
  2. customwas used without further purification in the following step

출처 및 근거

ORD 기록
ord-2fafa5b6418f48e9972a2ce2156309a0
출처 데이터셋
uspto-grants-2012_09
특허 번호
US08273782B2

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