4-[2-methyl-4-(5-methyl-1,2,4-oxadiazol-3-yl)phenyl]benzoic Acid → HCID 18980075, 화합물

반응식

[CH3:1][C:2]1[CH:7]=[C:6]([C:8]2[N:12]=[C:11]([CH3:13])[O:10][N:9]=2)[CH:5]=[CH:4][C:3]=1[C:14]1[CH:19]=[CH:18][C:17]([C:20](O)=[O:21])=[CH:16][CH:15]=1.[N:23]1([CH2:29][CH2:30][O:31][C:32]2[CH:33]=[C:34]([CH:36]=[CH:37][C:38]=2[O:39][CH3:40])[NH2:35])[CH2:28][CH2:27][O:26][CH2:25][CH2:24]1>>[N:23]1([CH2:29][CH2:30][O:31][C:32]2[CH:33]=[C:34]([NH:35][C:20]([C:17]3[CH:18]=[CH:19][C:14]([C:3]4[CH:4]=[CH:5][C:6]([C:8]5[N:12]=[C:11]([CH3:13])[O:10][N:9]=5)=[CH:7][C:2]=4[CH3:1])=[CH:15][CH:16]=3)=[O:21])[CH:36]=[CH:37][C:38]=2[O:39][CH3:40])[CH2:28][CH2:27][O:26][CH2:25][CH2:24]1

참가 물질

반응물 2

HCID 111301684-[2-methyl-4-(5-methyl-1,2,4-oxadiazol-3-yl)phenyl]benzoic Acid

HCID 186726704-Methoxy-3-[2-(morpholin-4-yl)ethoxy]aniline

생성물 1

HCID 18980075HCID 18980075, 화합물

실험 절차

The title compound was prepared from 2'-methyl-4'-(5-methyl-1,2,4-oxdiazol-3-yl)biphenyl-4-carboxylic acid (EP 0533268 A1) and 3-(2-morpholin-4-ylethoxy)-4-methoxyaniline (D13) using a similar procedure to Example 1 (58%) mp 58°-63° C.

출처 및 근거

ORD 기록: ord-f82a561804a24620acf9b6dede5a0d00
출처 데이터셋: uspto-grants-1998_09
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US05801170

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