4-tert-Butylbenzoyl chloride → N-(4-t-Butylbenzoyl)-4-(2-bromoethyl)benzenesulfonamide

HRID 2392982노트

반응식

HRID 2392982 반응식
[Br:1][CH2:2][CH2:3][C:4]1[CH:9]=[CH:8][C:7]([S:10]([NH2:13])(=[O:12])=[O:11])=[CH:6][CH:5]=1.[C:14]([C:18]1[CH:26]=[CH:25][C:21]([C:22](Cl)=[O:23])=[CH:20][CH:19]=1)([CH3:17])([CH3:16])[CH3:15]>C1(C)C(C)=CC=CC=1>[C:14]([C:18]1[CH:19]=[CH:20][C:21]([C:22]([NH:13][S:10]([C:7]2[CH:6]=[CH:5][C:4]([CH2:3][CH2:2][Br:1])=[CH:9][CH:8]=2)(=[O:11])=[O:12])=[O:23])=[CH:25][CH:26]=1)([CH3:17])([CH3:15])[CH3:16]

참가 물질

4

반응물 2

HCID 743724-tert-Butylbenzoyl chlorideHCID 144850914-(2-Bromoethyl)benzenesulfonamide

생성물 1

HCID 18977847N-(4-t-Butylbenzoyl)-4-(2-bromoethyl)benzenesulfonamide

시약·촉매·용매 1

HCID 7237O-Xylene용매

실험 절차

A mixture of 26.41 g (0.10 mol) of 4-(2-bromoethyl)benzenesulfonamide, 19.67 g (0.10 mol) of 4-t-butylbenzoyl chloride and 160 ml of xylene was heated at reflux for 20 hrs. The hot solution was cooled and the solid which crystallized was collected, recrystallized from isopropanol collected, washed with ligroine and dried.

후처리

  1. temperaturewas heated
  2. temperatureat reflux for 20 hrs
  3. temperatureThe hot solution was cooled
  4. customthe solid which crystallized
  5. customwas collected
  6. customrecrystallized from isopropanol
  7. customcollected
  8. washwashed with ligroine
  9. customdried

출처 및 근거

ORD 기록
ord-23c317b380a94066a46fe7c4f084d972
출처 데이터셋
uspto-grants-1998_09
특허 번호
US05804348

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