HCID 18979130, 화합물 → HCID 18979236, 화합물

HRID 2393180노트

반응식

HRID 2393180 반응식
[NH2:1][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[CH:5]=[CH:4][C:3]=1[CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][C:18]([O:20]COC)=O.[NH2:24][OH:25].CO>[Cl-].[NH4+]>[NH2:1][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[CH:5]=[CH:4][C:3]=1[CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][C:18]([NH:24][OH:25])=[O:20]

참가 물질

4

반응물 2

HCID 18979130HCID 18979130, 화합물HCID 86645014HCID 86645014, 화합물

생성물 1

HCID 18979236HCID 18979236, 화합물

시약·촉매·용매 1

HCID 25517Ammonium Chloride용매

실험 절차

The methoxymethyl 7-(1-amino-2-naphthyl)heptanoate (0.3 g) was added to 1M hydroxylamine/methanol (2.85 ml) and the mixture was stirred at room temperature for 1.5 hours. This reaction mixture was poured in saturated aqueous ammonium chloride solution and extracted with ethyl acetate. The organic layer was washed with water, dried, and concentrated to dryness, and the residue was recrystallized from hexane-ether to provide the title compound (0.116 g).

후처리

  1. extractionextracted with ethyl acetate
  2. washThe organic layer was washed with water
  3. customdried
  4. concentrationconcentrated to dryness
  5. customthe residue was recrystallized from hexane-ether

출처 및 근거

ORD 기록
ord-9b0415ea17bb4a90b9bd1176d9006b47
출처 데이터셋
uspto-grants-1998_09
특허 번호
US05804601

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