Hydrogen Peroxide → HCID 18975618, 화합물

HRID 2393341노트

반응식

HRID 2393341 반응식
OO.[Cl:3][C:4]1[CH:9]=[CH:8][C:7]([Cl:10])=[CH:6][C:5]=1[N:11]1[CH2:15][CH2:14][C:13](=[O:16])[NH:12]1.[Se](=O)=O.O>C(O)(=O)C>[Cl:3][C:4]1[CH:9]=[CH:8][C:7]([Cl:10])=[CH:6][C:5]=1[N:11]1[CH:15]=[CH:14][C:13](=[O:16])[NH:12]1

참가 물질

6

반응물 4

HCID 784Hydrogen PeroxideHCID 962WaterHCID 24007Selenium DioxideHCID 18975619HCID 18975619, 화합물

생성물 1

HCID 18975618HCID 18975618, 화합물

시약·촉매·용매 1

HCID 176Acetic Acid용매

실험 절차

Hydrogen peroxide (30% solution in water, 120 ml) is slowly added to a well stirred suspension of 1-(2,5-dichlorophenyl)-3-pyrazolidone (200 g, 0.86 mol) and selenium dioxide (3.0 g) in acetic acid (1000 ml). The temperature is controlled by cooling, not to exceed +50° C. After stirring at this temperature for 1 hour crushed ice and water is added. The product is filtered and dried yielding 1-(2,5-dichlorophenyl)-3-pyrazolone, m.p. 201°-202° C.

후처리

  1. temperatureby cooling
  2. customto exceed +50° C
  3. stirringAfter stirring at this temperature for 1 hour
  4. additionis added
  5. filtrationThe product is filtered
  6. customdried

출처 및 근거

ORD 기록
ord-3fbcc38e111545ba88ab131c7a53ef2b
출처 데이터셋
uspto-grants-1998_09
특허 번호
US05807863

반응 노트

불러오는 중…