Diethyl Ether → Methyl (1,2-benzoxazol-3-yl)acetate

HRID 2393476노트

반응식

HRID 2393476 반응식
[O:1]1[C:5]2[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=2[C:3]([CH2:10][C:11]([OH:13])=[O:12])=[N:2]1.[CH3:14]COCC>CO>[O:1]1[C:5]2[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=2[C:3]([CH2:10][C:11]([O:13][CH3:14])=[O:12])=[N:2]1

참가 물질

4

반응물 2

HCID 3283Diethyl EtherHCID 3017292-(1,2-Benzoxazol-3-yl)acetic acid

생성물 1

HCID 2763403Methyl (1,2-benzoxazol-3-yl)acetate

시약·촉매·용매 1

HCID 887Methanol용매

실험 절차

A solution of 1,2-benzisoxazole-3-acetic acid (prepared according to G. Casini et al, J. Het. Chem. 6, 1969, 279) (18 g), ether saturated with dry HCI (150 ml) and methanol (200 ml) was stirred for 2 h at room temperature. Removal of the volatiles in vacuo gave methyl 1,2-benzisoxazole-3-acetate (17 g) as an oil.

후처리

  1. customRemoval of the volatiles in vacuo

출처 및 근거

ORD 기록
ord-db6d7adc09e14f29a3511edf5e8e5cf2
출처 데이터셋
uspto-grants-1998_09
특허 번호
US05807871

반응 노트

불러오는 중…