Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3,5-Bis(trifluoromethyl)benzylamine → 2,4-Dichloro-5-N-[3',5'-bis(trifluoromethyl)benzyl]pyrimidine-5-carboxamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 3,5-Bis(trifluoromethyl)benzylamine | HCID 521099 | — |
| 반응물 | 2,4-Dichloropyrimidine-5-carbonyl chloride | HCID 13784112 | — |
| 생성물 | 2,4-Dichloro-5-N-[3',5'-bis(trifluoromethyl)benzyl]pyrimidine-5-carboxamide | HCID 18972871 | 61% |
반응 단계
The title compound was prepared as described in Example 1, but employing 2,4-dichloropyrimidine-5-carbonylchloride (0.10 g, 0.40 mmol) and 3,5-bistrifluoromethylbenzylamine (0.10 g, 0.45 mmol) to give the compound in a 61% yield (0.12 g); m.p. 144°-145° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05811428 |
| 출처 데이터셋 | uspto-grants-1998_09 |
| ORD ID | ord-bfa6358ca7434fa7b349859c0648527c |
| 출처 메모 | uspto-grants-1998_09 |