5-Bromo-2-methyl-2-pentene → 1-(4-Methyl-3-pentenyl)indole-4-carbaldehyde

반응식

Br[CH2:2][CH2:3][CH:4]=[C:5]([CH3:7])[CH3:6].[NH:8]1[C:16]2[CH:15]=[CH:14][CH:13]=[C:12]([CH:17]=[O:18])[C:11]=2[CH:10]=[CH:9]1>>[CH3:6][C:5]([CH3:7])=[CH:4][CH2:3][CH2:2][N:8]1[C:16]2[CH:15]=[CH:14][CH:13]=[C:12]([CH:17]=[O:18])[C:11]=2[CH:10]=[CH:9]1

참가 물질

반응물 2

HCID 1375215-Bromo-2-methyl-2-pentene

HCID 333703Indole-4-carboxaldehyde

생성물 1

HCID 189735511-(4-Methyl-3-pentenyl)indole-4-carbaldehyde수율 86.9%

실험 절차

The same procedures used in Example 7 were repeated except for using 4.59 g of 5-bromo-2-methyl-2-pentene and 2.00 g of indole-4-carbaldehyde as a starting material to give 2.72 g of 1-(4-methyl-3-pentenyl)indole-4-carbaldehyde as a brown oily substance. The yield thereof was found to be 87%.

출처 및 근거

ORD 기록: ord-81dbeea5ecfd4b8eb08457c4f13944f0
출처 데이터셋: uspto-grants-1998_09
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US05811439

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