Pyridine → Benzaldehyde (2-cyanoethyl)(ethoxycarbonyl)hydrazone

HRID 2394487노트

반응식

HRID 2394487 반응식
Cl[C:2]([O:4][CH2:5][CH3:6])=[O:3].[C:7]([CH2:9][CH2:10][NH:11][N:12]=[CH:13][C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1)#[N:8].N1C=CC=CC=1>C(OCC)(=O)C>[C:7]([CH2:9][CH2:10][N:11]([C:2]([O:4][CH2:5][CH3:6])=[O:3])[N:12]=[CH:13][C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1)#[N:8]

참가 물질

5

반응물 3

HCID 1049PyridineHCID 10928Ethyl chloroformateHCID 85132177Benzaldehyde (2-cyanoethyl)hydrazone

생성물 1

HCID 54133299Benzaldehyde (2-cyanoethyl)(ethoxycarbonyl)hydrazone

시약·촉매·용매 1

HCID 8857Ethyl Acetate용매2회

실험 절차

1.08 g (10-2 moles) of ethyl chloroformate in solution in 5 ml of anhydrous ethyl acetate are added dropwise to a solution containing 10-2 moles of benzaldehyde (2-cyanoethyl)hydrazone and 0.79 g (10-2 moles) of anhydrous pyridine in 20 ml of anhydrous ethyl acetate, with stirring in the cold. The reaction mixture is slowly heated to reflux temperature and left stirring for 2 hours and then filtered hot.

후처리

  1. temperatureThe reaction mixture is slowly heated
  2. temperatureto reflux temperature
  3. waitleft
  4. stirringstirring for 2 hours
  5. filtrationfiltered hot

출처 및 근거

ORD 기록
ord-71ed5e1fe11941278fc16793dd5381b3
출처 데이터셋
uspto-grants-1998_09
특허 번호
US05811456

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