Methyl 4-[2-(2-benzyloxyphenyl)ethyl]-3-aminobenzoate → Methyl 4-[3-(2-benzyloxyphenyl)propyl]-2-hydroxybenzoate
반응식
[CH2:1]([O:8][C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][C:10]=1[CH2:15][CH:16]=[CH:17][C:18]1[CH:27]=[CH:26][C:21]([C:22]([O:24][CH3:25])=[O:23])=[C:20]([OH:28])[CH:19]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.C(OC1C=CC=CC=1CCC1C=CC(C(OC)=O)=CC=1N)C1C=CC=CC=1.C(OC1C=CC=CC=1C=CC1C=CC(C(OC)=O)=CC=1[N+]([O-])=O)C1C=CC=CC=1>>[CH2:1]([O:8][C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][C:10]=1[CH2:15][CH2:16][CH2:17][C:18]1[CH:27]=[CH:26][C:21]([C:22]([O:24][CH3:25])=[O:23])=[C:20]([OH:28])[CH:19]=1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1참가 물질
4
실험 절차
Methyl 4-[3-(2-benzyloxyphenyl)propyl]-2-hydroxybenzoate was prepared from methyl 4-[3-(2-benzyloxyphenyl)propenyl]-2-hydroxybenzoate by the method described in Example 9 for the synthesis of methyl 4-[2-(2-benzyloxyphenyl)ethyl]-3-aminobenzoate from methyl 4-[2-(2-benzyloxyphenyl)ethenyl]-3-nitrobenzoate.