HCID 18776682, 화합물 → 4-(Quinolin-2-yloxy)aniline

HRID 2395347노트

반응식

HRID 2395347 반응식
[N+:1]([C:4]1[CH:20]=[CH:19][C:7]([O:8][C:9]2[CH:18]=[CH:17][C:16]3[C:11](=[CH:12][CH:13]=[CH:14][CH:15]=3)[N:10]=2)=[CH:6][CH:5]=1)([O-])=O>C(OCC)(=O)C.[Pd]>[NH2:1][C:4]1[CH:5]=[CH:6][C:7]([O:8][C:9]2[CH:18]=[CH:17][C:16]3[C:11](=[CH:12][CH:13]=[CH:14][CH:15]=3)[N:10]=2)=[CH:19][CH:20]=1

참가 물질

4

반응물 1

HCID 18776682HCID 18776682, 화합물

생성물 1

HCID 131089464-(Quinolin-2-yloxy)aniline

시약·촉매·용매 2

HCID 23938Palladium촉매HCID 8857Ethyl Acetate용매

실험 절차

2-(4-Nitrophenoxy)quinoline(3 mmoles, 0.82 g) was dissolved in 100 ml ethyl acetate and hydrogenated over 2.0 g 5% Pd/C at room temperature for 1 hr. The solution was filtered through cellulose and concentrated to yield 2-(4-aminophenoxy)quinoline 0.58, 82%. Mass Spec (FD) 236. Calculated for C15H12N2O: C, 76.25; H, 5.12, N, 11.86. Found: C, 75.97; H, 5.37; N, 11.83.

후처리

  1. filtrationThe solution was filtered through cellulose
  2. concentrationconcentrated

출처 및 근거

ORD 기록
ord-83a4f417128242fa872e93d7ff39af4f
출처 데이터셋
uspto-grants-1998_09
특허 번호
US05814646

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