Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Rolipram → 1-(6-Fluoroquinolin-2-ylmethyl)-4-[3-(cyclopentyloxy)-4-methoxyphenyl]pyrrolidinone
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Rolipram | HCID 5092 | — |
| 반응물 | 2-(Chloromethyl)-6-fluoroquinoline | HCID 11241007 | — |
| 생성물 | 1-(6-Fluoroquinolin-2-ylmethyl)-4-[3-(cyclopentyloxy)-4-methoxyphenyl]pyrrolidinone | HCID 18971748 | — |
반응 단계
Reaction of 4-[3-(cyclopentyloxy)-4-methoxyphenyl]pyrrolidinone with 2-chloromethyl-6-fluoroquinoline, analogous to the procedure of Example 29, yielded the title compound. M.P.: 65°-68° C. High Resolution Mass Spectra: Calc'd: 434.1983. Found: 434.2005.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05814651 |
| 출처 데이터셋 | uspto-grants-1998_09 |
| ORD ID | ord-dcc912890d2a40a783f98d42569334ef |
| 출처 메모 | uspto-grants-1998_09 |