Potassium Iodide → HCID 21437252, 화합물
반응식
[I-].[K+].[Cl:3][C:4]1[CH:5]=[CH:6][C:7]2[N:13]3[C:14]([CH2:17]Cl)=[N:15][N:16]=[C:12]3[CH2:11][N:10]=[C:9]([C:19]3[C:24]([F:25])=[CH:23][CH:22]=[CH:21][C:20]=3[F:26])[C:8]=2[CH:27]=1.C[NH:29]C1CC1.O1[CH2:37][CH2:36][CH2:35][CH2:34]1>>[Cl:3][C:4]1[CH:5]=[CH:6][C:7]2[N:13]3[C:14]([CH2:17][NH:29][CH2:34][CH:35]4[CH2:37][CH2:36]4)=[N:15][N:16]=[C:12]3[CH2:11][N:10]=[C:9]([C:19]3[C:24]([F:25])=[CH:23][CH:22]=[CH:21][C:20]=3[F:26])[C:8]=2[CH:27]=1참가 물질
5
실험 절차
In the manner given in Example 2, potassium iodide and 8-chloro-1-(chloromethyl)-6-(2,6-difluorophenyl)-4H-s-triazolo[4,3-a][1,4]benzodiazepine in tetrahydrofuran is treated with methylcyclopropylamine to give 8-chloro-1-[(cyclopropylmethylamino)methyl]-6-(2,6-difluorophenyl)-4H-s-triazolo[4,3-a][1,4]benzodiazepine.