Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Sodium hydride → 1-(2-Methylbenzoyl)-3-[2-(2-cyclohexylmethylpiperidino)ethyl]-5-methoxy-2-methylindole
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Sodium hydride | HCID 24758 | — |
| 반응물 | 2-Methylbenzoyl chloride | HCID 70276 | — |
| 반응물 | Sodium | HCID 5360545 | — |
| 반응물 | 3-[2-(2-Cyclohexylmethylpiperidino)ethyl]-5-methoxy-2-methylindole | HCID 21313365 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 생성물 | 1-(2-Methylbenzoyl)-3-[2-(2-cyclohexylmethylpiperidino)ethyl]-5-methoxy-2-methylindole | HCID 21313328 | — |
반응 단계
1-(2-Methylbenzoyl)-3-[2-(2-cyclohexylmethylpiperidino)ethyl]-5-methoxy-2-methylindole is prepared by reaction of 3-[2-(2-cyclohexylmethylpiperidino)ethyl]-5-methoxy-2-methylindole with sodium hydride in DMF and reaction of the resulting sodium salt with 2-methylbenzoyl chloride following the procedure described above in Example 1.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04021431 |
| 출처 데이터셋 | uspto-grants-1977_05 |
| ORD ID | ord-d1b5b4ca11d542c18a2fbc24639e9f88 |
| 출처 메모 | uspto-grants-1977_05 |