Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Propionic anhydride → 6-chloro-2-ethyl-1H-imidazo[4,5-b]quinoxaline
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Propionic anhydride | HCID 31263 | — |
| 반응물 | 6-Chloroquinoxaline-2,3-diamine | HCID 12517390 | — |
| 용매 | Tetrahydrofuran | HCID 8028 | — |
| 생성물 | 6-chloro-2-ethyl-1H-imidazo[4,5-b]quinoxaline | HCID 178437541 | — |
반응 단계
Four parts of 6-chloro-2,3-diaminoquinoxaline was combined with 3 parts of propionic anhydride in 2 parts of tetrahydrofuran. The mixture was heated for three hours during which time a thick slurry formed. The solid was collected from the hot mixture by filtration and washed twice with two parts of tetrahydrofuran. The gray solid was air-dried to give four parts of 6-chloro-2-ethyl-1H-imidazo[4,5-b]quinoxaline, m.p. 298°-300°.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04022777 |
| 출처 데이터셋 | uspto-grants-1977_05 |
| ORD ID | ord-9e35a6b9f5a54dd29f6ad807ad3dde7b |
| 출처 메모 | uspto-grants-1977_05 |