Sulfuric Acid → 2-Amino-4-chloropyridin-3-ol

HRID 2397840노트

반응식

HRID 2397840 반응식
[Cl:1][C:2]1[CH:7]=[CH:6][N:5]=[C:4]([NH:8][N+]([O-])=O)[CH:3]=1.S(=O)(=O)(O)[OH:13].NC1C([N+]([O-])=O)=C(Cl)C=CN=1>>[NH2:8][C:4]1[C:3]([OH:13])=[C:2]([Cl:1])[CH:7]=[CH:6][N:5]=1

참가 물질

4

반응물 3

HCID 1118Sulfuric AcidHCID 40716944-Chloro-3-nitropyridin-2-amineHCID 13040387HCID 13040387, 화합물

생성물 1

HCID 214366972-Amino-4-chloropyridin-3-ol

실험 절차

The reaction of 4-chloro-2-nitraminopyridine with concentrated sulfuric acid at 40° gives, according to Example I-2, 2-amino-4-chloro-3-nitropyridine. The procedure of Example I-2 is then followed with this intermediate to give 2-amino-4-chloro- 3-pyridinol.

후처리

  1. customgives

출처 및 근거

ORD 기록
ord-3dee309a5df641588e23c73906863629
출처 데이터셋
uspto-grants-1977_05
특허 번호
US04022897

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