Ammonia → 2,6-Dinitro-4-(trifluoromethyl)aniline
반응식
Cl[C:2]1[C:7]([N+:8]([O-:10])=[O:9])=[CH:6][C:5]([C:11]([F:14])([F:13])[F:12])=[CH:4][C:3]=1[N+:15]([O-:17])=[O:16].[NH3:18].C(O)C>C(OCC)(=O)C>[NH2:18][C:2]1[C:7]([N+:8]([O-:10])=[O:9])=[CH:6][C:5]([C:11]([F:14])([F:13])[F:12])=[CH:4][C:3]=1[N+:15]([O-:17])=[O:16]참가 물질
5
실험 절차
Twent-six grams (0.096m) of crude 4-chloro-3,5-dinitrobenzotrifluoride, 150 ml. of liquid ammonia and 150 ml. of 2B ethanol were heated in a sealed autoclave at 100° C. for about 4 hours. After cooling and venting, the reaction mixture was taken up in ethyl acetate. The ethyl acetate phase was washed with water. The ethyl acetate solution was dried and evaporated in vacuo to yield crude 4-amino-3,5-dinitrobenzotrifluoride.
후처리
- temperatureAfter cooling
- washThe ethyl acetate phase was washed with water
- dry with materialThe ethyl acetate solution was dried
- customevaporated in vacuo
출처 및 근거
- ORD 기록
- ord-c60c7e4201af4ff28c9f168523854eed
- 출처 데이터셋
- uspto-grants-1977_05
- 특허 번호
- US04024142
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