Benzene, 1-chloro-3-isocyanato- → N-(3-Chlorophenyl)-N'-(1,3-dimethyl-4-oxoimidazolidin-2-ylidene)urea

HRID 2398580

반응식

HRID 2398580 반응식
[CH3:1][N:2]1[CH2:6][C:5](=[O:7])[N:4]([CH3:8])[C:3]1=[NH:9].[Cl:10][C:11]1[CH:12]=[C:13]([N:17]=[C:18]=[O:19])[CH:14]=[CH:15][CH:16]=1>O1CCCC1>[Cl:10][C:11]1[CH:12]=[C:13]([NH:17][C:18]([N:9]=[C:3]2[N:4]([CH3:8])[C:5](=[O:7])[CH2:6][N:2]2[CH3:1])=[O:19])[CH:14]=[CH:15][CH:16]=1

참가 물질

4

반응물 2

HCID 17968Benzene, 1-chloro-3-isocyanato-HCID 140604272-Imino-1,3-dimethylimidazolidin-4-one

생성물 1

HCID 54371002N-(3-Chlorophenyl)-N'-(1,3-dimethyl-4-oxoimidazolidin-2-ylidene)urea

시약·촉매·용매 1

HCID 8028Tetrahydrofuran용매

실험 절차

A mixture of 6.35 g (0.050 mole) of 1,3-dimethyl-2-iminoimidazolidin-4-one, 7.85 g (0.050 mole) of 3-chlorophenylisocyanate and 75 ml of dry tetrahydrofuran is stirred at room temperature for four hours. The solution is evaporated in vacuo and the residue is crystallized from acetonitrile. Two recrystallizations from acetonitrile - ether gives pure product, 1-(3-chlorophenyl)-3-(1,3-dimethyl-4-oxo-2-imidazolidinylidene)urea, m.p. 134°-137° C.

후처리

  1. customThe solution is evaporated in vacuo
  2. customthe residue is crystallized from acetonitrile
  3. customTwo recrystallizations from acetonitrile - ether

출처 및 근거

ORD 기록
ord-fc23527607c04377a272ee457c95ad26
출처 데이터셋
uspto-grants-1977_05
특허 번호
US04025517

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